Dave Sannino

Postdoc,

lab rat.

IMG_2251 crop.JPEG

I’m a microbiologist by training, but I work across both sides of animal-bacteria symbioses.

Bacteria live in the gut, but they affect the function of tissues systemically, throughout their animal hosts. I’m interested in how bacterial metabolites plug in to host metabolism, and the consequences for metabolic health and lifespan. Making those precise connections ought to help us to predict and engineer microbiota with the right functions to promote longevity, without costs like adiposity.

C.V.

2020 

Volunteer laboratory scientist at the Lighthouse Lab in Glasgow, Glasgow, Scotland

2018 - 2019

Postdoctoral Associate in Neuroscience.

Vartanian Lab, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.

2017 - 2018 

Postdoctoral Research Assistant.

Angert Lab, Microbiology Department, Cornell University, Ithaca, NY, USA.

2017

PhD.

Major field: Microbiology.

Minor fields: Genetics, biochemistry.

Cornell University, Ithaca, NY, USA.

Advisors: Esther Angert, Nicolas Buchon, John Helmann.

2012 - 2013

Graduate Research Assistant.

Microbiology Department, Cornell University, Ithaca, NY, USA.

2011 - 2012

Graduate Research Assistant.

Microbiology Department, Cornell University, Ithaca, NY, USA.

Rotations in the Douglas, Angert and Ahner labs.

2010 - 2011

Laboratory technician.

Microbiology Department, Bini Lab, Rutgers University, New Brunswick, NJ, USA.

2010

Bachelor of Arts.

Major field: Biological Sciences (Summa cum laude).

Rutgers University, New Brunswick, NJ, USA.

2009 - 2010

Undergraduate researcher. 

Microbiology Department, Bini Lab, Rutgers University, New Brunswick, NJ, USA. 

Publications

  1. Edwards, KA, Randall EA, Tu-Maung, N, Sannino, DR, Feder, S, Angert, ER, and CE Kraft (2019). Periplasmic binding protein-based magnetic isolation and detection of thiamine in complex biological matrices. Talanta DOI 10.1016/j.talanta.2019.120168.

  2. Sannino, DR, Kraft, CE, Edwards, KA, and ER Angert (2018). Thiaminase I provides a growth advantage by salvaging precursors from environmental thiamin and its analogs in Burkholderia thailandensis. Applied and Environmental Microbiology DOI 10.1128/AEM.01268-18.

  3. Sannino, DR, Dobson, AJ, Edwards, KA, Angert, ER, and N Buchon (2018). The Drosophila melanogaster gut microbiota provisions thiamine to its host. mBio DOI 10.1128/mBio.00155-18.

  4. Sannino, DR and ER Angert (2017). Genomic insights into the thiamin metabolism of Paenibacillus thiaminolyticus NRRL B-4156 and P. apiarius NRRL B-23460. Standards in Genomic Sciences DOI 10.1186/s40793-017-0276-9.

  5. Hutchison, E, Yager, NA, Taw, MN, Taylor, M, Arroyo, F, Sannino, DR, and ER Angert (2017). Developmental stage influences chromosome segregation patterns and arrangement in the extremely polyploid, giant bacterium Epulopiscium sp. type B. Molecular Microbiology DOI 10.1111/mmi.13860.

  6. Dobson, AJ, Chaston, JM, Newell, PD, Donahue, L, Hermann, SL, Sannino, DR, Westmiller, S, Wong, AC, Clark, AG, Lazzaro, BP, and AE Douglas (2015). Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster. Nature Communications DOI 10.1038/ncomms7312.

  7. Newell, PD, Chaston, JM, Wang, Y, Winans, NJ, Sannino, DR, Wong, AC, Dobson, AJ, Kagle, J, and AE Douglas (2014). In vivo function and comparative genomic analyses of the Drosophila gut microbiota identify candidate symbiosis factors. Frontiers in Microbiology DOI 10.3389/fmicb.2014.00576.

  8. Honarbakhsh, M, Villafane, AA, Ruhl, I, Sannino, DR, and E Bini (2012). Development of a thermostable β-glucuronidase-based reporter system for monitoring gene expression in hyperthermophiles. Biotechnology and bioengineering DOI 10.1002/bit.24432.

  9. Villafane, AA, Voskoboynik, Y, Ruhl, I, Sannino, DR, Maezato, Y, Blum, P, and E Bini (2011). CopR of Sulfolobus solfataricus represents a novel class of archaeal-specific copper-responsive activators of transcription. Microbiology DOI 10.1099/mic.0.051862-0.

  10. Cuebas, M, Sannino, DR, and E Bini (2011). Isolation and characterization of arsenic resistant Geobacillus kaustophilus strain from geothermal soils. Journal of Basic Microbiology DOI 10.1002/jobm.201000314.